Block 5 · Molecules to Organisms · MCAS Reporting Category 1
Molecules to Organisms
This is the biggest slice of MCAS — cell types and organelles, the four macromolecules, membrane transport, and cellular energy. If you know cells, biomolecules, transport, and energy, you know Reporting Category 1.
What you need to know cold
- prokaryoteA cell with no nucleus — its DNA floats freely inside. = no nucleus (bacteria). eukaryoteA cell with a nucleus and membrane-bound organelles inside. = has a nucleusThe control center of a eukaryotic cell — holds the DNA. (animals, plants, fungi).
- mitochondriaThe organelle that makes ATP — the cell's energy source. make atpThe energy molecule — powers nearly everything cells do. (energy). chloroplastThe organelle in plant cells where photosynthesis happens. does photosynthesisPlants use light, CO2, and water to make glucose and oxygen.. Ribosomes make proteinA large molecule made of amino acids — does many jobs in cells..
- All organic molecules have carbon as the backbone.
- Words ending in -ose = carbohydrateA sugar or starch molecule — the body's quick energy source.. Words ending in -ase = enzymeA protein that speeds up a chemical reaction in the body..
- diffusionThe spreading of particles from where there are many to where there are few. = high to low, no energy. osmosisThe diffusion of water across a membrane — high to low. = water diffusing. active-transportMoving molecules against the gradient — requires ATP energy. = low to high, needs ATP.
- photosynthesisPlants use light, CO2, and water to make glucose and oxygen. and cellular-respirationCells break down glucose with oxygen to make ATP energy. are opposites. Products of one = reactants of the other.
- Photosynthesis: CO₂ + H₂O + light → glucoseA simple sugar — the building block of carbohydrates. + O₂ (in the chloroplastThe organelle in plant cells where photosynthesis happens.).
- Cellular respiration: glucose + O₂ → CO₂ + H₂O + atpThe energy molecule — powers nearly everything cells do. (in the mitochondriaThe organelle that makes ATP — the cell's energy source.).
The Big Rule for this block
Carbon is the backbone. Enzymes speed things up. Energy flows from light → glucose → ATP.
If the question says "speeds up a reaction," the answer is enzyme. If it says "against the gradient" or "pump," the answer is active transport. If it asks where energy comes from, trace the chain: sunlight → photosynthesis → glucose → cellular respiration → ATP.
Key vocabulary in 8 languages
Words from this block. Use the row in your home language to help your memory. Many of these words are similar across languages because they come from Greek and Latin roots.
| English | Español | Português | Français | Italiano | Kreyòl | Tiếng Việt | العربية |
|---|---|---|---|---|---|---|---|
| prokaryote | procariota | procarionte | procaryote | procariote | pwokaryòt | sinh vật nhân sơ | بدائي النواة(badāʾī an-nawāh) |
| eukaryote | eucariota | eucarionte | eucaryote | eucariote | ekaryòt | sinh vật nhân thực | حقيقي النواة(ḥaqīqī an-nawāh) |
| ribosome | ribosoma | ribossomo | ribosome | ribosoma | ribozòm | ribosome / ribôxôm | ريبوسوم(rībūsūm) |
| mitochondria | mitocondria | mitocôndria | mitochondrie | mitocondrio | mitokondri | ty thể | ميتوكندريا(mītūkundriyā) |
| chloroplast | cloroplasto | cloroplasto | chloroplaste | cloroplasto | kloroplas | lục lạp | بلاستيدة خضراء(blāstīda khaḍrāʾ) |
| protein | proteína | proteína | protéine | proteina | pwoteyin | protein / prô-tê-in | بروتين(brūtīn) |
| enzyme | enzima | enzima | enzyme | enzima | anzim | enzym / enzim | إنزيم(inzīm) |
| carbohydrate | carbohidrato | carboidrato | glucide / hydrate de carbone | carboidrato | kabidrat | cacbohiđrat / gluxit | كربوهيدرات(karbūhīdrāt) |
| lipid | lípido | lipídio | lipide | lipide | lipid | lipid | ليبيدات / دهون(lībīdāt / duhūn) |
| glucose | glucosa | glicose | glucose | glucosio | glikoz | glucose / glucôzơ | جلوكوز / غلوكوز(jlūkūz / ghulūkūz) |
| diffusion | difusión | difusão | diffusion | diffusione | difizyon | khuếch tán | انتشار(intishār) |
| osmosis | ósmosis | osmose | osmose | osmosi | osmoz | thẩm thấu | تناضح / الخاصية الأسموزية(tanāḍuḥ) |
| active transport | transporte activo | transporte ativo | transport actif | trasporto attivo | transpò aktif | vận chuyển chủ động | نقل نشط(naql nashiṭ) |
| photosynthesis | fotosíntesis | fotossíntese | photosynthèse | fotosintesi | fotosentèz | quang hợp | البناء الضوئي(al-bināʾ al-ḍawʾī) |
| respiration | respiración celular | respiração celular | respiration cellulaire | respirazione cellulare | respirasyon selilè | hô hấp tế bào | تنفس خلوي(tanaffus khalawī) |
| ATP | ATP | ATP | ATP | ATP | ATP | ATP | ATP(ATP) |
All rows in this table are sourced from the Quick Reference Section 1 vocabulary, which was verified through Ms Brandolini's GPT-5 / Gemini cycle (Vietnamese and Arabic) or relies on cognate consistency (Romance languages and Haitian Kreyòl).
The full picture
Molecules to Organisms — cells, biomolecules, transport, and energy
What this reading is about
"Molecules to Organisms" is MCAS Reporting Category 1 — the biggest slice of the test. It covers everything from the parts of a cell to how cells get energy. This block reviews four sub-topics in one pass:
- Cell types and organelleA small part inside a cell that does a specific job. functions.
- The four macromolecules and enzymeA protein that speeds up a chemical reaction in the body. rules.
- How things cross the cell-membraneThe flexible outer boundary of every cell — controls what enters and leaves. (transport).
- How cells make and use energy (photosynthesisPlants use light, CO2, and water to make glucose and oxygen. and cellular-respirationCells break down glucose with oxygen to make ATP energy.).
Part 1: Cells
Two kinds of cells
Every living thing is made of cells. There are two main types:
- prokaryoteA cell with no nucleus — its DNA floats freely inside. — no nucleusThe control center of a eukaryotic cell — holds the DNA.. DNA floats freely. Bacteria are prokaryotes. They are small and simple.
- eukaryoteA cell with a nucleus and membrane-bound organelles inside. — has a nucleus. DNA is inside the nucleus. Animals, plants, and fungi are eukaryotes. They are bigger and more complex.
Key organelles
Eukaryotic cells have organelles — small parts inside the cell, each with a specific job:
- nucleusThe control center of a eukaryotic cell — holds the DNA. — the control center. Holds the DNA.
- Ribosome — makes proteinA large molecule made of amino acids — does many jobs in cells.. Found in ALL cells (prokaryotes too).
- mitochondriaThe organelle that makes ATP — the cell's energy source. — makes atpThe energy molecule — powers nearly everything cells do. (energy). The inner membrane has folds for more surface area. Found in both plant and animal cells.
- chloroplastThe organelle in plant cells where photosynthesis happens. — does photosynthesisPlants use light, CO2, and water to make glucose and oxygen.. Found only in plant cells.
- cell-membraneThe flexible outer boundary of every cell — controls what enters and leaves. — the flexible outer boundary of every cell. Controls what enters and leaves.
Part 2: Macromolecules
The four types
All living things are built from four types of large molecules. All of them have carbon as the backbone — carbon is what makes a molecule "organic."
- carbohydrateA sugar or starch molecule — the body's quick energy source. — sugars and starches. Building block: glucoseA simple sugar — the building block of carbohydrates. (a monosaccharide). Quick energy. Words ending in -ose = carbohydrate.
- lipidA fat or oil — stores energy and makes up cell membranes. — fats and oils. Building block: fatty acid + glycerol. Long-term energy storage and cell membranes.
- proteinA large molecule made of amino acids — does many jobs in cells. — does many jobs (enzymes, antibodies, structure). Building block: amino acid.
- Nucleic acid — DNA and RNA. Building block: nucleotide. Holds genetic information.
Enzymes
An enzymeA protein that speeds up a chemical reaction in the body. is a protein that speeds up a chemical reaction. Words ending in -ase are enzymes (lipase, sucrase, amylase). Enzymes work best at one specific temperature — too hot or too cold and they stop working. On a graph, enzyme activity looks like a bell curve.
Part 3: Transport across the membrane
The cell-membraneThe flexible outer boundary of every cell — controls what enters and leaves. is selectively permeable — it lets some things through but not everything. There are three main ways molecules cross:
- diffusionThe spreading of particles from where there are many to where there are few. — molecules move from HIGH concentration to LOW concentration. No energy needed. Small molecules (like O₂) can pass right through.
- osmosisThe diffusion of water across a membrane — high to low. — the diffusion of water across a membrane. Still high to low, still no energy.
- active-transportMoving molecules against the gradient — requires ATP energy. — molecules move from LOW to HIGH concentration (against the gradient). Requires atpThe energy molecule — powers nearly everything cells do. energy and a protein pump. The sodium-potassium pump is the classic example.
Part 4: Cellular energy
The two equations
These two processes are opposites. The products of one are the reactants of the other:
- photosynthesisPlants use light, CO2, and water to make glucose and oxygen.: 6 CO₂ + 6 H₂O + light energy → glucoseA simple sugar — the building block of carbohydrates. + 6 O₂. Happens in the chloroplastThe organelle in plant cells where photosynthesis happens..
- cellular-respirationCells break down glucose with oxygen to make ATP energy.: glucose + 6 O₂ → 6 CO₂ + 6 H₂O + atpThe energy molecule — powers nearly everything cells do.. Happens in the mitochondriaThe organelle that makes ATP — the cell's energy source..
Plants do BOTH — photosynthesis during the day (when there is light) and cellular respiration all the time. Animals only do cellular respiration.
Connecting it all
These four sub-topics connect. Cells need energy → energy comes from cellular respiration → respiration needs glucose → plants make glucose via photosynthesis → photosynthesis happens in chloroplasts (organelles) → the glucose and oxygen cross the membrane via transport. One topic feeds the next.
Diagram: a prokaryote (no nucleus)
A prokaryote is a bacterium. The DNA floats free — there is no nucleus. You can also see a cell wall, a capsule around the outside, and a long whip called a flagellum for moving. If the test shows a cell with no nucleus and free-floating DNA, pick prokaryote.
Diagram: a eukaryote (has a nucleus)
A eukaryote has a real nucleus holding the DNA, plus little machines inside called organelles — the mitochondria (makes ATP), the ribosomes (build proteins), and others. Plant cells and animal cells are both eukaryotes. Plant cells also have a cell wall and chloroplasts; animal cells do not.
Diagram: inside a mitochondrion
The mitochondrion is where cellular respiration happens — where the cell makes ATP. The inside membrane is folded, and those folds give more surface area. More surface area = more room to do the reaction = more ATP. If the test shows a folded inner membrane, the answer is about ATP and surface area.
Diagram: a carbohydrate is a chain of rings
A carbohydrate is a chain of six-sided rings. Each ring is one glucose. Many glucose rings linked together = a carbohydrate like starch or glycogen. If the picture shows a row of six-sided rings, the answer is carbohydrate, and the building block is glucose.
Diagram: enzymes have an optimal temperature
An enzyme works best at one temperature — usually around body temperature. If it gets too cold, the enzyme slows down. If it gets too hot, the enzyme is denatured (broken) and stops working altogether. On a graph of activity vs temperature this makes a bell curve with one peak. If the test shows a bell curve, the answer is about optimal temperature and denaturing.
Diagram: active transport (uses ATP)
In active transport, a protein pump moves molecules across the membrane from LOW concentration to HIGH concentration — the wrong direction. Going the wrong way costs energy, so the cell spends ATP. If the picture shows a pump and molecules going LOW → HIGH, the answer is active transport.
Diagram: photosynthesis and respiration are opposites
The two reactions are a cycle. The products of one are the reactants of the other. Photosynthesis takes in CO₂, water, and light, and makes glucose and O₂. Cellular respiration takes that glucose and O₂ and breaks it back down to CO₂ and water — and releases ATP. Light goes in; ATP comes out. Everything else loops.
Pictures to recognize on the test
| The picture shows… | The answer is… |
|---|---|
| Cell with NO nucleus, has flagella + capsule + free DNA. | Prokaryote (bacterium). |
| Cell WITH nucleus, chloroplast, cell wall. | Plant cell (eukaryote). |
| Cell WITH nucleus, NO chloroplast, NO cell wall. | Animal cell (eukaryote). |
| Mitochondrion with folded inner membrane. | The folds = surface area = more ATP. |
| Chain of repeating six-sided rings. | Carbohydrate. Building block = glucose. |
| Bell-curve graph (enzyme activity vs temperature). | Enzyme works best at one temperature; too hot or cold = stops. |
| Membrane with protein pump, molecules going LOW → HIGH. | Active transport (uses ATP). |
| Equation: 6 CO₂ + 6 H₂O + X → glucose + 6 O₂. | X = light energy (photosynthesis). |
Pattern rules
| If the question says… | Pick… |
|---|---|
| "Which is a prokaryote?" + image with NO nucleus. | The bacteria-looking one (free DNA + flagella). |
| "Backbone of organic compounds" or "most important element for macromolecules." | Carbon. |
| Word ending in -ose (glucose, fructose, sucrose). | Carbohydrate. |
| "Speeds up a reaction" or word ending in -ase. | Enzyme. |
| "Sodium-potassium pump energy source" or anything with "pump" + energy. | ATP. |
| HIGH → LOW, no protein needed. | Simple diffusion. |
| LOW → HIGH, with protein pump. | Active transport (pick BOTH "low to high" AND "protein pump"). |
| "What process speeds up during exercise to make ATP?" | Cellular respiration. |
Where to practice
Practice the Block 5 — Molecules to Organisms test on Pear Assessment. You can retake it as many times as you want — the questions and answer choices shuffle each time, so every attempt feels a little different. Try it without looking at this page first. If you get stuck, come back, look up the pattern, then try again.